Company cases about Key Criteria for High-Quality Cryopreserved Mice in Research

Key Criteria for High-Quality Cryopreserved Mice in Research

2026-01-15

High-quality cryopreserved mice are essential for ensuring reproducibility and reliability in biomedical research. Superior specimens are defined by three core attributes:

First, Genetic Integrity: The mice must be of a verified, pure genetic background, with confirmed genotype and absence of genetic drift or contamination.
Second, Optimal Viability Post-Thaw: Specimens must exhibit high post-thaw recovery rates, including excellent sperm motility (for sperm) or oocyte/embryo morphology, ensuring successful fertilization or embryo transfer.
Third, Stringent Process Control: Quality is determined by rigorous procedural standards. This includes the use of proven cryoprotectants, controlled-rate freezing protocols, and secure storage in liquid nitrogen with continuous temperature monitoring.

Additionally, comprehensive documentation—spanning lineage, health status, and full cryopreservation logs—is mandatory. Specimens meeting these criteria guarantee the preservation of valuable genetic material, maximize experimental success, and uphold the highest standards in scientific research.
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